Towards Precision Medicine through biomathematical modeling
of a human body

DNA sequencing is the process of identifying the order of nucleotide bases (adenine, thymine, cytosine, and guanine) in a strand of DNA. Nowadays, with the appropriate equipment and resources, sequencing a short segment of DNA is a relatively straightforward task. The sequence of these nucleotides in the genome is what defines one's genetic makeup. We leverage this sequence for an in-depth analysis of a patient's genetic traits, primarily to assess susceptibility to various diseases, metabolization of different substances, and reaction to established medications. To achieve this, we draw upon extensive datasets not only from our own research but also from the collective body of work contributed by other researchers. Using this information, we construct a genetic profile for the patient.

We view the human body, and beyond, as an intricately complex and finely-tuned system. Within this system, every organ, set of organs, and subsystems are intricately linked to one another through a vast network of connections, both direct and via other components of the system. To dissect and simulate the processes operating within this system, we develop a biomathematical model of the human body. Subsequently, we refine this model with insights gleaned from the patient's genetic profile. This yields a tailored biomathematical model specific to each patient.

At this stage, we closely monitor the patient's health status through the analysis of biochemical data and, if necessary, daily medical telemetry. This allows us to fine-tune the patient's biomathematical model. Additionally, we keep a record of and promptly address any significant deviations in vital signs. When notable discrepancies in key health indicators are identified, Artificial Intelligence conducts a comprehensive analysis of the extensive body of information and collective medical expertise specific to the given case and patient. This process aims to pinpoint the underlying cause or reasons for these deviations and provide an initial diagnosis. Think of it as a consultation involving a vast panel of doctors, assisting your primary physician in swiftly and accurately arriving at a final diagnosis, without protracted deliberations.

If a disease is identified, the patient's biomathematical model is employed to simulate the ailment and its impact on both individual organs and the overall body. This simulation enables us to precisely pinpoint the root cause of the issue, factoring in the patient's genetic predispositions. This holds true even if outward symptoms manifest in an organ associated with the underlying source and subject to its influence. Furthermore, simulation is employed to replicate the progression of a disease under specific treatment protocols and gauge the response to various medications. We also factor in potential side effects on related organs and the entire body.

In the world, there exists an extensive array of medicines and treatment methods. Yet, they all rely on statistical data regarding their efficacy and potential side effects. Precision Medicine, founded on the individual genetic data of the patient, enables us to attain the utmost effectiveness of medications while steering clear of adverse impacts on the patient's body. Our solutions empower us to pinpoint precisely these medications or formulate a distinct combination tailored to the specific patient, drawing from the genetic traits of their body.